Haemodynamic changes from baseline to the first follow-up catheterisation (3–18 months) in patients with portopulmonary hypertension treated with inhaled iloprost or bosentan
| Iloprost# | Bosentan¶ | Between group difference | |||
| Baseline | 6–18 months | Baseline | 6–18 months | ||
| RAP mmHg Change (p-value) | 7±6 | 11±8 | 8±6 | 4±3 | p = 0.040 |
| 4±11 (p = 0.320) | -4±5 (p = 0.027) | ||||
| ―Ppa mmHg Change (p-value) | 50±10 | 53±8 | 53±8 | 45±13 | p = 0.077 |
| 2±8 (p = 0.577) | -7±13 (p = 0.077) | ||||
| CO L·min−1 Change (p-value) | 4.8±1.6 | 4.7±1.7 | 4.4±1.2 | 5.7±1.3 | p = 0.060 |
| 0±1.8 (p = 0.765) | 1.2±1.1 (p = 0.002) | ||||
| PVR dyn Change (p-value) | 828±349 | 895±351 | 925±473 | 579±261 | p = 0.022 |
| 73±457 (p = 0.413) | -345±361 (p = 0.008) | ||||
| Sv,O2 % Change (p-value) | 65±9 | 62±11 | 61±7 | 68±5 | p = 0.064 |
| -3±13 (p = 0.966) | 6±8 (p = 0.005) | ||||
Data are presented as mean±sd, unless otherwise stated. RAP: right atrial pressure; ―Ppa: mean pulmonary artery pressure; CO: cardiac output; PVR: pulmonary vascular resistance; Sv,O2: mixed venous oxygen saturation. #: n = 11; ¶: n = 13. 1 mmHg = 0.133 kPa.