Table 5—

Results of laboratory analyses at follow-up of patients who had sarcoidosis in childhood

VariableSubjects nMedian (range)Reference intervalAbnormal n
Plasma total calcium mmol·L−1352.52 (2.21–2.73)2.20–2.603#
Plasma ionised calcium mmol·L−1321.25 (1.19–1.41)1.17–1.341
Plasma IgG μmol·L−13373 (43–95)41–99
Plasma IgA μmol·L−13312.4 (4.0–23.1)4.4–22.82+
Plasma IgM μmol·L−1330.93 (0.29–1.92)0.41–2.192§
Plasma IgE kIU·L−12912 (2–412)0–1002ƒ
SACE U·L−12848 (25–130)30–1151##
Serum soluble interleukin-2 receptor U·L−128469 (317–1660)223–7104¶¶
  • Ig: immunoglobulin; SACE: serum angiotensin-converting enzyme. #: one female with hypercalcaemia at diagnosis also had high ionised calcium at follow-up and was otherwise healthy, one female and one male without hypercalcaemia at diagnosis had normal ionised calcium at follow-up and were healthy; : one female with hypercalcaemia at diagnosis was healthy at follow-up; +: one male with high IgA and healthy, one male with low IgA (patient 8) and healthy; §: one male with low IgM (patient 8) and healthy, one male with low IgM (patient 1) with steroid-treated chronic active pulmonary sarcoidosis; ƒ: one female with sarcoid diabetes insipidus and no allergy (patient 5), one female with chronic active stage III pulmonary sarcoidosis and no allergy (patient 6); ##: one female with chronic active stage III pulmonary sarcoidosis (patient 6); ¶¶: one female with serum soluble interleukin-2 receptor (S-sIL-2R) 876 U·L−1, SACE 113 U·L−1, chronic active stage I pulmonary sarcoidosis and diabetes insipidus and not on steroids (patient 5), one female with S-sIL-2R 1112 U·L−1, SACE 32 U·L−1, chronic active stage IV pulmonary sarcoidosis and intestinal sarcoidosis and was not on steroids, one female (patient 6) with S-sIL-2R 1280 U·L−1, SACE 130 U·L−1 with chronic active stage III pulmonary sarcoidosis and nephrocalcinosis and not on steroids, one male (patient 1) with S-sIL-2R 1680 U·L−1, SACE 85 U·L−1 with chronic active stage I pulmonary sarcoidosis and on steroids.