Table 2—

Acute haemodynamic changes in response to sildenafil#

Major acute effect groupMinor acute effect group
Subjects n3532
Δpa %23±113±2
ΔPVR %34±112±2
  • Data are presented as mean±sem, unless otherwise stated. Classification of the acute response was according to the degree of reduction in pulmonary vascular resistance (PVR; cut-off 27%). Δ: change; pa: mean pulmonary arterial pressure. #: in a subset of 67 patients.