Weighted kappa coefficients(κw) between thoracic high-resolution computed tomography (HRCT) reviewers#
Mean κw | κw (95% CI) | |||
A versus B | A versus C | B versus C | ||
Total | 0.40 | 0.40 (0.29–0.52) | 0.33 (0.23–0.44) | 0.46 (0.36–0.56) |
OLB/TLB: UIP | ||||
Absent | 0.41 | 0.47 (0.03–0.92) | 0.24 (-0.21–0.69) | 0.52 (0.19–0.86) |
Present | 0.35 | 0.35 (0.16–0.54) | 0.21 (0.03–0.40) | 0.49 (0.33–0.66) |
Total reviewed | 0.40 | 0.41 (0.24–0.58) | 0.27 (0.11–0.43) | 0.53 (0.38–0.67) |
TBLB/no biopsy | 0.40 | 0.40 (0.24–0.56) | 0.40 (0.26–0.54) | 0.39 (0.26–0.53) |
FVC | ||||
<60% pred | 0.40 | 0.36 (0.16–0.56) | 0.33 (0.15–0.51) | 0.50 (0.34–0.67) |
>60% pred | 0.39 | 0.42 (0.28–0.56) | 0.33 (0.20–0.46) | 0.43 (0.30–0.56) |
CI: confidence interval; OLB: open lung biopsy; TLB: thoracoscopic lung biopsy; UIP: usual interstitial pneumonia; TBLB: transbronchial lung biopsy; FVC: forced vital capacity; % pred: % predicted. #: each reviewer (A, B and C) scored the HRCT scans as unlikely, probable or very suggestive for the diagnosis of UIP.