Table 7—

Summary of various chronic obstructive pulmonary disease(COPD) outcomes from patient-reported outcomes

Outcome measurePatient-reported outcomes
QoL-RIQAQ20BPQMRF-28CCQPFSDQ-MPFSSEADLLCADLQWB
Standardisation of methodologyYesYesYesYesYesYesYesYesYesYes
Statistical frequency distribution
 In the general populationnananananananananaYes
 In COPD patientsnaYesYesYesYesnanananana
ReproducibilitynanaYesnanaYesYesnaYesYes
Relationship with health outcomes
 In the general populationNANANANANANANANANANA
 In COPD patientsNANANANANANANANANANA
Sensitivity to treatment effectnanaYes/nonananananaYesYes/no
Utility in COPD exacerbationsnananananananananana
Influence on comorbiditiesPossiblePossiblePossiblePossiblePossiblePossiblePossibleYesPossibleYes
Utility in multicentre trialsPossiblePossiblePossiblePossiblePossibleYesnaYesYesYes
Measurement requirements
 QuestionnaireYesYesYesYesYesYesYesYesYesYes
 EquipmentNANANANANANANAnanaYes
 Time-consumingna3 minnana2 min15–20 min15 min5–10 minna10–20 min
 TrainingYesYesYesYesYesYesYesYesYesYes
Measurement costnaFreeFreenanananananaFee req.
Safety issuesNoNoNoNoNoNoNoNoNoNo
Ethical issuesNoNoNoNoNoNoNoNoNoNo
  • QoL-RIQ: Quality of Life For Respiratory Illness Questionnaire; AQ20: Airways Questionnaire 20; BPQ: Breathing Problems Questionnaire; MRF-28: Maugeri Foundation Respiratory Failure Questionnaire; CCQ: Clinical Control Questionnaire; PFSDQ-M: Pulmonary Functional Status and Dyspnoea Questionnaire; PFSS: Pulmonary Functional Status Scale; EADL: Nottingham Extended Activity of Daily Living Scale; LCADL: London Chest Activity of Daily Living Scale; QWB: Quality of Well-Being Scale; na: not available; NA: not applicable; Fee req.: licence fee requested.