Baseline characteristics | |
Subjects | 90 |
Age months | 14.9 (6.8–25.8) |
Males/females | 68/22 (76/24) |
Gestational age# weeks | 40.00 (36.57–42.43) |
Birth weight g | 3585 (2040–4600) |
Main complaints | |
Cough | 50 (56) |
Wheeze | 13 (14) |
Dyspnoea | 17 (19) |
Sputum production | 10 (11) |
Duration of symptoms months | 7 (2–18) |
History of wheezing¶ | 71 (79) |
1 episode of wheezing | 18 (20) |
2 episodes of wheezing | 24 (27) |
≥3 episodes of wheezing | 29 (32) |
Hospital admission for wheezing | 24 (27) |
History of RSV bronchiolitis+ | 11 (12) |
Family history of asthma§ | 48 (53) |
Family history of allergyƒ | 75 (83) |
Atopic eczema## | 28 (31) |
Skin-prick test positive¶¶ | 20 (22) |
Atopy++ | 36 (40) |
Food allergy§§ | 21 (23) |
Exposure to tobacco smoke | 31 (34) |
Maternal smoking | 22 (24) |
Furry animals at home | 22 (24) |
Data are presented as n, n (%) and median (range). RSV: respiratory syncytial virus. #: data available for 89 children; ¶: at least one episode of physician-confirmed wheeze; +: wheezing lower respiratory tract illness with RSV infection proven by antigen detection; §: physician-diagnosed asthma in a first degree relative; ƒ: physician-diagnosed allergy in a first degree relative; ##: current diagnosis made by a paediatrician; ¶¶: a wheal with a diameter ≥3 mm against at least one of the tested allergens; ++: presence of atopic eczema and/or skin-prick test positivity; §§: diagnosis confirmed by a positive food challenge.