Table 3—

Correlation between tuberculin reaction size and the net-spot counts in T-Spot.TB test among the whole cohort before and after stratification by age and smoking

GroupSubjects nESAT6 wellCFP10 well
Correlation#p-valueCorrelation#p-value
Whole cohort1340.336<0.0010.243<0.01
Age <65 yrs910.324<0.010.2530.02
Age ≥65 yrs430.422<0.010.1970.21
Current smokers320.0300.87-0.0960.60
Never- or ex-smokers1020.375<0.0010.308<0.001
  • ESAT: early secretary antigenic target; CFP: culture filtrate protein. #: Spearman’s rank correlation coefficients between the tuberculin reaction size and the net spot count (test well count−negative control well count) of T-Spot.TB test.