Table 1—

Summary of investigations performed in subjects with abnormal bronchoscopic findings

Subject	Diagnosis	Lung function % pred		Methacholine challenge	Oesophageal pH/impedance monitoring		ENT examination
Subject	Diagnosis	FEV₁	FVC	Methacholine challenge	Reflux episodes^#	Demeester score^¶	ENT examination
1	TPO	117	112	Negative	72	0.8	Normal
2	TPO	94	108	Mildly positive	Not tolerated⁺	Not tolerated⁺	Normal
3	TPO	107	115	Negative	112	3.1	Normal
4	TPO	82	98	Negative	78	6.4	Post-nasal drip
5	TPO	107	107	Negative	78	1.4	Post-nasal drip
6	TPO	93	112	Mildly positive	62	9.4	Normal
7	TPO	110	111	Negative	56	3.9	Normal
8	Long uvula	135	136	Negative	2	0.4	Normal
9	Amyloidosis	95	98	Negative	Not tolerated^§	Not tolerated^§	Post-nasal drip

% pred: % predicted; ENT: ear, nose and throat; FEV₁: forced expiratory volume in one second; FVC: forced vital capacity; TPO: tracheobronchopathia osteochondroplastica. ^#: normal can be defined as <73 episodes; ^¶: normal can be defined as a score <14.7; ⁺: mild gastritis at gastroscopy and, therefore, treated for acid reflux disease; ^§: gastroscopy showed minimal peristalsis and biopsy confirmed amyloid infiltration.