Table 1—

Correlates of pulmonary hypertension

Variablepa <25 mmHgpa ≥25 mmHgpa >40 mmHgp-value#p-value
Subjects n1362932231
 Age yrs54.0±8.753.4±8.549.9±9.20.040<0.0001
 BMI kg·m−227.7±4.828.7±5.127.7±5.2<0.00010.870
Pulmonary function
 FVC % pred49.6±15.748.4±16.751.4±20.80.0200.610
 FEV1 % pred52.7±16.550.0±16.551.5±19.0<0.00010.30
 Pa,CO2 mmHg40.5±5.741.2±6.938.7±7.80.150<0.001
 6-min walk distance <45 m10.313.921.10.010<0.0001
 Any need for O275.986.092.8<0.0001<0.0001
 Any need for ≥3 L·min−1 O237.351.465.4<0.0001<0.0001
 O2 used L·min−12.3±1.92.9±2.13.5±2.4<0.0001<0.0001
Functional status
 Some or total ADL assistance56.763.374.40.001<0.0001
 In intensive care unit1.
Comorbid illnesses
Haemodynamic monitoring
 Cardiac index L·min−1·m−22.8±0.72.8±0.82.5±0.90.82<0.0001
Ppcw mmHg8.3±4.212.1±5.514.0±8.2<0.0001<0.0001
  • Data are presented as mean±SD or %, unless otherwise stated. pa: mean pulmonary artery pressure; BMI: body mass index; FVC: forced vital capacity; % pred: % predicted; FEV1: forced expiratory volume in one second; Pa,CO2: carbon dioxide arterial tension; ADL: activities of daily living; COPD: chronic obstructive pulmonary disease; Ppcw: pulmonary capillary wedge pressure. #: pa >25 versus ≤25 mmHg; : pa >40 versus ≤25 mmHg. n = 2,525. 1 kPa = 0.133 mmHg.