Table 3—

Chromosomal regions showing significant(p≤0.01) multipoint logarithm of odds (LOD) scores for at least one phenotype#

MarkerPosition cMAsthma scoreAsthma severityFEV1 (% pred)
LODp-valueLODp-valueLODp-value
D1S4684.201.520.004
D1S21414.001.160.01
D2S30538.901.460.005
D2S16547.401.800.002
D2S126221.101.590.003
D4S40556.951.210.009
D5S42895.401.220.009
D6S46089.801.640.003
D7S5315.281.190.01
D7S5177.141.140.01
D7S2465180.41.000.01
D14S7040.111.200.009
D18S46431.172.060.001
D18S5341.242.400.0004
D18S47852.861.370.006
  • #: in 110 Epidemiological study on the Genetics and Environment of Asthma, bronchial hyperresponsiveness and atopy (EGEA) families; : of linkage peak, based on Marshfield map. cM; centimorgan; FEV1: forced expiratory volume in one second; % pred: % predicted.