Subject characteristics
| Controls | COPD | ||
| Cachectic | Noncachectic | ||
| M/F n | 6/3 | 4/3 | 4/3 |
| Age yrs | 65±4 | 58±13 | 67±9 |
| Height cm | 166.1±7.6 | 168.0±10.5 | 167.2±7.2 |
| Body composition | |||
| Weight kg | 74.7±10.4 | 59.0±8.8# | 72.5±11.7 |
| BMI kg·m−2 | 27.1±3.7 | 20.1±1.3# | 27.0±3.4 |
| FFM kg | 50.5±9.1 | 43.2±5.9¶ | 48.8±8.05 |
| FFMI kg·m−2 | 18.0±2.3 | 14.8±0.7# | 17.3±2.2 |
| FM kg | 23.3±8.1 | 15.8±4.1¶ | 23.7±6.4 |
| FMI kg·m−2 | 8.4±3.5 | 5.4±1.2# | 8.9±2.2 |
| Lung function | |||
| FVC % pred | 100.4±20.5** | 74.0±15.4 | 79.8±17.5 |
| FEV1 % pred | 117.2±19.8** | 38.8±11.6 | 41.4±18.5 |
| DL,CO % pred | 83.6±29.2* | 43.3±18.8 | 60.9±29.0 |
| Smoking pack-yrs | 35±17 | 27±14 | 35.7±5 |
| Pa,O2 kPa | 9.7±0.8 | 9.0±1.5 | 9.4±1.1 |
| Pa,CO2kPa | 5.2±0.4 | 5.3±0.7 | 5.2±0.9 |
Data are presented as mean±sd, unless otherwise stated. COPD: chronic obstructive pulmonary disease; M: male; F: female; BMI: body mass index; FFM: fat-free mass; FFMI: fat-free mass index; FM: fat mass; FMI: fat mass index; FVC: forced vital capacity; % pred: % predicted; FEV1: forced expiratory volume in one second; DL,CO: diffusing capacity of the lung for carbon monoxide; Pa,O2: arterial oxygen tension; Pa,CO2: arterial carbon dioxide tension. #: p<0.01 versus noncachectic patients; ¶: p<0.05; *: p<0.05; **: p<0.01 versus COPD patients.