Table 4—

Interleukin-13 receptor α1 subunit -281T/1365A haplotype association with atopy and asthma phenotypes in asthmatic family members

MotherFatherFirst sisterFirst brother
Subjects n10085216245
Log total IgE#0.0490.1600.7680.600
FEV1 % pred0.7530.2000.8320.856
BHR slope0.4200.8080.8700.442
Atopy severity score0.7000.3000.6400.432
Asthma severity score0.1200.5710.8300.956
  • Data presented are p-values, unless otherwise stated. Ig: immunoglobulin; FEV1: forced expiratory volume in one second; % pred: % predicted; BHR: bronchial hyperresponsiveness. #: age-corrected; : FEV1 response to methacholine.