Table 3—

Details of outcomes measured in the three studies presented in the pooled analysis of smokersversus ex-smokers

SubjectsnMean difference (95% CI)p-value#
FEV1 pred %1011.94 (-4.35–8.32)+0.43
FVC L101-0.18 (-0.50–0.14)0.26
FEV1/FVC %1010.02 (-0.20–0.06)0.31
CD8 count§101-0.18 (-0.50–0.14)0.26
CD68 count§1010.02 (-0.02–0.06)0.31
Neutrophil count§1010.13 (-0.28–0.54)0.54
CD4 count§100-0.25 (-0.67–0.16)0.23
TNF-α count§1010.03 (-0.38–0.45)0.88
EG2 count§450.38 (-0.04–0.80)0.07
Mast cell count§500.38 (-0.05–0.81)0.09
  • Cell counts were expressed in cells·mm−2 in the study by Gamble et al. 11 and in cells·mm−1 in the other two studies 3, 10. CI: confidence interval; FEV1: forced expiratory volume in one second; % pred: % predicted; FVC: forced vital capacity; TNF: tumour necrosis factor. #: smokers versus ex-smokers; : weighted mean difference; +: 99% CI; §: standardised mean difference.