Table 4—

Categorical variables significantly associated with colistin-susceptible ventilator-associated pneumonia (VAP) in univariate and multivariate analysis

Univariate analysisMultivariate analysis
OR (95% CI)p-valueβ-coefficient (95% CI)p-value
Duration of mechanical ventilation >30 days17.7 (1.7–179.4)0.016
Overall hospitalisation >50 days17.7 (1.7–179.4)0.001
Overall ICU stay >40 days20.5 (2.0–205.5)<0.00131.6 (31.5–495.9)0.014
Characteristics present at VAP onset
 Duration of prior antimicrobial therapy >10 days31.5 (2.9–340.4)<0.00113.2 (2.2–78.7)0.005
 Time from admission to VAP diagnosis >16 days27.1 (2.7–269.5)<0.001
 Previous episode of VAP27.7 (2.8–273.5)<0.0016.0 (1.0–35.7)0.047
 Prior use of carbapenems21.7 (2.2–212.9)<0.001
  • OR: odds ratio; CI: confidence interval; ICU: intensive care unit.