Combined analysis for mean inspiratory flow(VT/tI) in chronic obstructive pulmonary disease nonrandomised controlled trials
First author [Ref.] | Favours bilevel n | Favours control n | MD±se | Weight % | MD (random) 95% CI |
Ambrosino 25 | 7 | 7 | 73.0000±64.1349 | 22.02 | 73.00 (−52.70–198.70) |
Highcock 18 | 8 | 8 | 149.0000±222.0434 | 1.84 | 149.00 (−286.20–584.20) |
Lien 26 | 11 | 11 | 30.0000±42.6401 | 49.81 | 30.00 (−53.57–113.57) |
Nava 17 | 6 | 7 | 145.0000±58.6399 | 26.34 | 145.00 (30.07–259.93) |
Total | 32 | 33 | 100 | 71.94 (12.96–130.92) |
MD: mean difference; CI confidence interval. Comparison: crossover trials of bilevel noninvasive positive pressure ventilation versus all modalities. Outcome: VT/tI mL·s−1. Test for heterogeneity: Chi squared = 2.64, df = 3 (p<0.45), I2 = 0%. Test for overall effect: Z = 2.39 (p = 0.02).