Table 4—

Combined analysis for arterial oxygen tension in chronic obstructive pulmonary disease nonrandomised controlled trials

First author [Ref.]Favours bilevel nFavours control nMD±seWeight %MD (random) 95% CI
Ambrosino 25775.0000±2.420118.225.00 (0.26–9.74)
Krachman 20663.6500±10.01772.263.65 (−15.98–23.28)
Lin 2710120.3000±1.350826.080.30 (−2.35–2.95)
Maragoni 28141413.2000±4.31779.3213.20 (4.74–21.66)
Meecham Jones 2914145.9000±2.703016.445.90 (0.60–11.20)
Nava 17675.1000±1.952221.515.10 (1.27–8.93)
Strumpf 30772.0000±5.65526.172.00 (−9.08–13.08)
Total64671004.49 (1.43–7.55)
  • MD: mean difference; CI: confidence interval. Comparison: crossover trials of bilevel noninvasive positive pressure ventilation versus all modalities. Outcome: arterial oxygen tension mmHg. Test for heterogeneity: Chi squared = 12.51, df = 6 (p = 0.05), I2 = 52.0%. Test for overall effect: Z = 2.88 (p = 0.004).