Table 10—

Dyspnoea ratings with bilevel noninvasive positive pressure ventilation use in chronic obstructive pulmonary disease

First author [Ref.]Scale usedTrial lengthBefore/after Rx/CLOutcome dataComments
RCTs
 Casanova 11BORG/MRCD1 yrRx5±1.63*/2*
CL4±1.63/2
 Clini 23MRCD at 0 months/12 months/24 months2 yrsRx3.3±0.3/2.7±0.8#/2.3±0.72
CL2.7±0.6/3.0±0.77/2.9±0.72
 Garrod 24CRDQ dyspnoea score8 weeksRx13.1 to 18.0***Data from the dyspnoea portion of the CRDQ instrument
CL15.1 to 16.8
 Renston 22BORG5 daysRx2.0±1.2 to 0.7±0.9**
CL1.8±1.13 to 1.3±1.13
Non-RCTs
 Strumpf 30Dyspnoea scale of Mahler6 monthsBefore0.6±1.7Functional impairment dyspnoea rating
After0.3±1.3
  • Data are presented as mean±sd. Rx: treatment; CL: control; BORG: Borg dyspnoea scale; MRCD: Medical Research Council dyspnoea scale; CRDQ: Chronic Respiratory Disease Questionnaire. #: p = 0.048 at 12 months; : p = 0.013 at 24 months. *p<0.05; **: p<0.01; ***: p<0.001.