Antibiotic regimens, clinical status, sputum inflammatory indices and quantitative bacterial load in stable cystic fibrosis patients chronically infected withPseudomonas aeruginosa
| Subject | Antibiotics | Sputum TCC ×106·mL−1 | Sputum iron μmol·L−1 | Sputum ferritin mg·L−1 | P. aeruginosa CFU·mL−1 | Anaerobic load CFU·mL−1 |
| 1 | Tobramycin nebs | 14.5 | 31 | 1480 | 3.8×106 | 2.6×106 |
| 2 | Tobramycin nebs | 10.2 | 21.8 | 1115 | 5.9×104 | 1.5×107 |
| 5# | Augmentin | 64 | 60 | 3380 | 2.6×108 | 2.7×106 |
| 10# | Colistin nebs | 4.7 | 34.2 | 3708 | 4.6×107 | 6.0×107 |
| 11 | Ciprofloxacin | 58.6 | 32 | 2930 | 9.4×105 | 1.6×107 |
| 13 | Bactrim | 79.7 | 41 | 2920 | 2.8×108 | 4.1×108 |
| 15 | Cycles augmentin and ciprofloxacin p.o., tobramycin nebs | 50.7 | 34 | 2060 | 6.5×107 | 3.5×107 |
| 16 | Cycles amoxycillin and flucloxacillin p.o. | 6.6 | 13 | 550 | 1.4×105 | 8.7×106 |
| 17 | Colistin nebs and augmentin p.o. | 20.0 | 20.8 | 1055 | 8.4×105 | 3.0×107 |
| 18 | Augmentin and flucloxacillin p.o., tobramycin nebs | 38.2 | 60 | 3640 | 2.0×108 | 2.0×106 |
| 19 | Colistin nebs | 8.2 | 57.6 | 7277 | 5.8×108 | 7.9×108 |
| 20 | Augmentin and flucloxacillin p.o., tobramycin nebs | 6.35 | 77 | 10610 | 8.2×107 | 1.0×108 |
| 21 | Tobramycin nebs | 0¶ | 78 | 5780 | 7.3×107 | 5.9×108 |
| 22 | Colistin nebs and augmentin p.o. | 15.3 | 19 | 1840 | 1.4×106 | 1.7×107 |
| 23 | Nil | 3.7 | 2.4 | 117 | 8.0×105 | 6.6×107 |
TCC: total cell counts; CFU: colony-forming units. #: patients 5 and 10 provided sputum samples during both stable and acute phases (>1 month apart); ¶: a logistical error in the laboratory resulted in a sputum TCC not being performed.