Table 2—

Mean annual change for different parameters in preschool# and schoolchildren

Preschool childrenSchoolchildren
Mean annual changep-valueMean annual changep-value
Interval+ yrs2.762.89
Height m0.0700.0000.0550.000
Weight kg2.840.0002.710.000
PFTs
Rint,exp Z-score0.050.780.150.182
 FEV1 % pred-1.620.125
 FVC % pred0.050.956
 FEV1/FVC-1.940.001
 MEF50% % pred-1.200.518
 FEF75% % pred-2.720.14
 FEF25–75% % pred-2.560.147
Radiograph score
 Chrispin–Norman0.850.0060.500.01
 Adjusted Chrispin–Norman1.070.0040.640.003
 Wisconsin0.350.0310.030.977
 Northern0.330.1100.110.34
 Brasfield-0.600.001-0.210.081
  • PFTs: pulmonary function tests; Rint,exp: expiratory interrupter resistance; FEV1: forced expiratory volume in one second; % pred: % predicted; FVC: forced vital capacity; MEF50%: maximal instantaneous forced flow when 50% of the FVC remains to be exhaled; FEF75%: forced expiratory flow at 75% of FVC; FEF25–75%: forced expiratory flow between 25 and 75% of FVC. #: n = 21; : n = 30; +: interval represents the mean time between visits 1 and 2.