Preschool children | Schoolchildren | |||
Mean annual change | p-value | Mean annual change | p-value | |
Interval+ yrs | 2.76 | 2.89 | ||
Height m | 0.070 | 0.000 | 0.055 | 0.000 |
Weight kg | 2.84 | 0.000 | 2.71 | 0.000 |
PFTs | ||||
Rint,exp Z-score | 0.05 | 0.78 | 0.15 | 0.182 |
FEV1 % pred | -1.62 | 0.125 | ||
FVC % pred | 0.05 | 0.956 | ||
FEV1/FVC | -1.94 | 0.001 | ||
MEF50% % pred | -1.20 | 0.518 | ||
FEF75% % pred | -2.72 | 0.14 | ||
FEF25–75% % pred | -2.56 | 0.147 | ||
Radiograph score | ||||
Chrispin–Norman | 0.85 | 0.006 | 0.50 | 0.01 |
Adjusted Chrispin–Norman | 1.07 | 0.004 | 0.64 | 0.003 |
Wisconsin | 0.35 | 0.031 | 0.03 | 0.977 |
Northern | 0.33 | 0.110 | 0.11 | 0.34 |
Brasfield | -0.60 | 0.001 | -0.21 | 0.081 |
PFTs: pulmonary function tests; Rint,exp: expiratory interrupter resistance; FEV1: forced expiratory volume in one second; % pred: % predicted; FVC: forced vital capacity; MEF50%: maximal instantaneous forced flow when 50% of the FVC remains to be exhaled; FEF75%: forced expiratory flow at 75% of FVC; FEF25–75%: forced expiratory flow between 25 and 75% of FVC. #: n = 21; ¶: n = 30; +: interval represents the mean time between visits 1 and 2.