Minor allele frequencies of single nucleotide polymorphisms(SNPs) in the study groups
| Gene | SNP | Rate of decline study | Baseline study | ||
| Nondecline | Fast decline | High function | Low function | ||
| IL10 | -627C/A | 23.1 | 20.9 | 22.1 | 20.6 |
| 734G/T | 48.7 | 52.9 | 49.8 | 51.7 | |
| 1668A/T | 28.3 | 27.0 | 28.1 | 26.0 | |
| 3368G/A | 14.9 | 19.1 | 14.6 | 15.8 | |
| IL10RA | 5850G/A | 30.8 | 30.9 | 31.8 | 30.5 |
| 6865A/G | 45.8 | 45.4 | 47.1 | 46.6 | |
| 6881A/G | 16.1 | 15.9 | 15.8 | 16.1 | |
| 9826A/G | 30.6 | 30.3 | 31.7 | 30.1 | |
| 11372A/G | 3.8 | 2.9 | 2.6 | 2.8 | |
| 12488G/A | 30.1 | 29.6 | 30.1 | 29.3 | |
| 14904A/G | 46.7 | 47.3 | 46.7 | 45.5 | |
IL10: interleukin (IL)-10 gene; IL10RA: IL-10 receptorα gene; C: cytosine; A: adenine; G: guanine; T: thymidine. p>0.05 for all in both studies in additive and codominant models.