The number of patients included in the Alpha One International Registry by country, last updated March 2006
| Country | Subjects n | First patient included yr |
| Total | 2627 | 1997 |
| Australia | 18 | 1997 |
| Germany | 340 | 1997 |
| Italy | 172 | 1997 |
| The Netherlands | 290 | 1997 |
| The Republic of South Africa | 12 | 1997 |
| UK | 552 | 1997 |
| Sweden | 343 | 1997 |
| Canada | 184 | 1999 |
| New Zealand | 151 | 1999 |
| USA | 25 | 2000 |
| Spain | 277 | 2001 |
| Austria | 98 | 2002 |
| Switzerland | 64 | 2002 |
| Belgium | 27 | 2003 |
| Argentina | 15 | 2004 |
| Denmark | 54 | 2006 |
| Poland | 3 | 2006 |
| Brazil | 2 | 2006 |