Table 2—

Isoprenaline potency(-logEC50) in the absence or presence of β2-adrenoceptor agonists on the isolated human bronchus

Drug concentrationSubjects n-logEC50
PSS67.48±0.08
PSS + indacaterol
 10−7 M67.20±0.16
 3×10−7 M67.81±0.15
PSS57.48±0.07
PSS + formoterol
 10−9 M57.59±0.16
 3×10−9 M57.05±0.23
PSS67.49±0.16
PSS + salmeterol
 10−7 M65.58±0.35*
 3×10−7 M65.24±0.44*
  • Data are expressed as mean±sem. PSS: physiological salt solution. *: p<0.05 versus control.