RVSP mmHg | SAP mmHg | RV/LV+S | Pa,O2 mmHg | |
Saline control | 29.9±1.8 | 118.9±23.1 | 0.30±0.02 | 202.8±12.9 |
MCT | ||||
2 week | 42.3±12.2 | 113.6±23.1 | 0.33±0.05 | 210.5±38.7 |
4 week | 63.5±11.4* | 105.5±21.7 | 0.54±0.09* | 143.4±29.0* |
Data are presented as mean±sd (n = 12 animals per group). RVSP: right ventricular systolic pressure; SAP: systemic arterial pressure; RV/LV+S: ratio of right ventricle mass to left ventricle plus septum mass; Pa,O2: arterial oxygen tension. *: p<0.05 for MCT-treated mice versus saline-treated control mice. 1 mmHg = 0.133 kPa.