Table 4—

Indications for cardiopulmonary exercise testing in clinical practice

IndicationRecommendation grade
Detection of exercise-induced bronchoconstrictionA
Detection of exercise-induced arterial oxygen desaturationB
Functional evaluation of subjects with unexplained exertional dyspnoea and/or exercise intolerance and normal resting lung and heart functionD
To recognise specific disease exercise response patterns that may help in the differential diagnosis of ventilatory versus circulatory causes of exercise limitationC
Functional and prognostic evaluation of patients with COPDB, C
Functional and prognostic evaluation of patients with ILDB, B
Functional and prognostic evaluation of patients with CFC, C
Functional and prognostic evaluation of patients with PPHB, B
Functional and prognostic evaluation of patients with CHFB, B
Evaluation of interventions
Maximal incremental testC
High-intensity constant work-rate “endurance” testsB
Prescription of exercise trainingB
  • With the use of this grading system, A is relatively rare and B is usually considered the best achievable. COPD: chronic obstructive pulmonary disease; ILD: interstitial lung disease; CF: cystic fibrosis; PPH: primary pulmonary hypertension; CHF: chronic heart failure.