Table 2—

Patient characteristics for patients with and without nontuberculous mycobacteria(NTM) cultured from their sputum during the study period

NTM-positiveNTM-negative
Patients1088
Age yrs59.4±3.359.3±1.4
Male428
FEV1 % pred59.9±8.663.9±2.3
FVC % pred86.0±6.985.8±2.0
CFTR mutations2× ΔF508 het 7× none 1× not known2× ΔF508 het 2× R117h het 73× none 11× not known
Colonisation
 P. aeruginosa641
 H. influenzae04
 S. aureus02
Long-term antibiotics
 Colomycin (nebulised)520
 Gentamicin (nebulised)03
 Amoxicillin (oral)23+1 nebulised
 Azithromycin (oral)#01
 Ciprofloxacin (oral)#01
 Clarithromycin (oral)#04
 Doxycycline (oral)#211
 Metronidazole (oral)01
 Flucloxacillin (oral)01
 Trimethoprim (oral)01
 None243
  • Data are presented as n or mean±sem. FEV1: forced expiratory volume in one second; % pred: percentage of predicted value; FVC: forced vital capacity; CFTR: cystic fibrosis transmembrane regulator; P. aeruginosa: Pseudomonas aeruginosa; H. influenzae: Haemophilus influenzae; S. aureus: Staphylococcus aureus; het: heterozygous. #: antibiotic can have antimycobacterial activity. Two NTM-negative patients were taking long-term colomycin and azithromycin and one was taking long-term colomycin and doxycycline. One NTM-positive patient was taking long-term colomycin and doxycycline.