Table 5—

Baseline characteristics of survival and predicted survival in idiopathic pulmonary arterial hypertension patients treated withi.v. epoprostenol, oral bosentan or subcutaneous (SC) treprostinil based on the National Institute of Health Registry

i.v. epoprostenol#,ƒOral bosentan¶,##SC treprostinil+i.v. epoprostenol§,¶¶Oral bosentan§,¶¶
Ppa mmHg61±1357±1659±1359±1557±15
Pra mmHg14±610±610±510±510±5
CI L·min-1·m-21.8±0.62.4±0.82.2±0.72.1±0.62.2±0.6
NYHA class
 I/II15 (9)53 (16)
 III75 (46)139 (82)262 (79)83 (100)83 (100)
 IV87 (54)15 (9)17 (5)
Survival rates yrs
 188, 5996, 6988, 6993++95++
 276, 4689, 5780, 5689++87++
 363, 3586, 4874, 4678++82++
 4 yrs56, NANA69, 38NANA
  • Data are presented as mean±sd, n (%). For survival rates data are presented as % observed, % predicted, unless otherwise stated. Ppa: mean pulmonary artery pressure; Pra: mean right atrial pressure; CI: cardiac index; NYHA: New York Heart Association; NA: not available. #: n = 162; : n = 169; +: n = 332; §: n = 83; ƒ: from reference 14; ##: from reference 16; ¶¶: from reference 20; ++: % observed.