Angiotensin-converting enzyme genotype distribution and clinical characteristics in patients with acute respiratory distress syndrome
| All | II | ID | DD | p-value | |
| Subjects n | 84 | 23 (27) | 36 (43) | 25 (30) | |
| Sex M/F | 43/41 | 11/12 (30/24) | 21/15 (35/46) | 11/14 (35/29) | 0.56 |
| Age at diagnosis yrs | 43±16 | 45±17 | 43±15 | 42±17 | 0.74 |
| LIS | 3.2±0.4 | 3.2±0.6 | 3.3±0.6 | 3.15±0.5 | 0.75 |
| BMI kg·m-2 | 26±6 | 25±4 | 27±6 | 24±4 | 0.17 |
| Pa,O2/FI,O2mmHg | 116±65 | 98±58 | 126±74 | 119±56 | 0.27 |
| PEEP mbar | 16±4 | 16±3 | 17±4 | 16±5 | 0.71 |
| SAPS | 50±17 | 49±19 | 49±16 | 51±19 | 0.88 |
| SOFA | 12±4 | 12±3 | 13±4 | 12±4 | 0.30 |
| Duration of stay days | 18 (2–174) | 22 (6–48) | 17 (3–73) | 16 (2–174) | 0.11 |
| Pneumonia | 56 | 19 | 22 | 15 | |
| Sepsis | 20 | 5 | 10 | 6 | |
| Trauma or aspiration | 8 | 2 | 4 | 2 | 0.9 |
Data are presented as n, n (%), mean±sd or median (range). I: insertion; D: deletion; M: male; F: female; LIS: lung injury score; BMI: body mass index; Pa,O2: arterial oxygen tension; FI,O2: inspiratory oxygen fraction; PEEP: positive end-expiratory pressure; SAPS: Simplified Acute Physiology Score; SOFA: sequential organ failure assessment. p-Values were calculated using the Chi-squared test for categorical variables, ANOVA for continuous parametric variables and the Kruskal–Wallis test for continuous nonparametric variables.