Table 4—

Effect size of repeatedly assessed parameters during vasodilator treatment

Change during treatmentp-valueEffect size
MLHF score-10 (-5– -15)<0.001-0.48
MLHF physical subscore-5 (-3– -7)<0.001-0.54
MLHF emotional subscore-2 (-1– -4)0.011-0.38
NYHA/WHO functional class-0.4 (-0.2– -0.7)<0.001-0.57
6-MWD m50 (16–83)0.0010.32
Borg scale-0.6 (0.3– -1.6)0.100.27
Right ventricular systolic pressure mmHg-6 (2– -14)0.130.25
  • Data are presented as mean (95% confidence interval), unless otherwise stated. MLHF: Minnesota Living with Heart Failure; NYHA/WHO: New York Health Association/World Health Organization; 6-MWD: 6-min walking distance. 1 mmHg = 0.133 kPa.