Table 2—

Summary of efficacy results from the Gaining Optimal Asthma controL(GOAL) study

Stratum 1Stratum 2Stratum 3
SFCFPp-valueSFCFPp-valueSFCFPp-value
ITT patients n548550585578576579
Patients# achieving WC status (phase I)383 (71)356 (65)0.039400 (69)302 (52)<0.001288 (51)188 (33)<0.001
Patients# achieving TC status (phase I)225 (42)169 (31)≤0.001189 (32)114 (20)<0.001106 (19)43 (8)<0.001
Patients#, ¶ achieving WC status (phase I + end of phase II)418 (78)380 (70)0.003436 (75)344 (60)<0.001350 (62)264 (47)<0.001
Patients#, ¶ achieving TC status (phase I + end of phase II)270 (50)217 (40)<0.001257 (44)163 (28)<0.001163 (29)88 (16)<0.001
  • Data are presented as n (%), unless otherwise stated. SFC: salmeterol/fluticasone propionate combination; FP: fluticasone propionate; ITT: intention to treat; WC: well-controlled; TC: total control. #: all subjects, excluding those with missing baseline forced expiratory volume in one second. : cumulative number of patients.