Baseline characteristics
| Characteristic | |
| Subjects n | 48 |
| Age yrs | 50 (46–54) |
| Sex (females) | 31 (65) |
| Diagnosis n | |
| Pulmonary arterial hypertension | 26 (54) |
| Idiopathic | 18 (38) |
| Associated with collagen vascular disease | 3 (6) |
| Associated with Eisenmenger syndrome | 2 (4) |
| Associated with HIV infection | 3 (6) |
| Chronic thromboembolic pulmonary hypertension | 22 (46) |
| MLHF score at baseline | 49 (43–55) |
| Physical subscore | 24 (21–27) |
| Emotional subscore | 10 (8–12) |
| NYHA/WHO functional class | 3.3 (3.1–3.5) |
| Class II | 5 (10) |
| Class III | 22 (46) |
| Class IV | 21 (44) |
| 6-MWD m | 362 (318–406) |
| Borg scale | 4.2 (3.5–4.9) |
| Right ventricular systolic pressure gradient mmHg | 67 (60–74) |
| Invasive haemodynamics# | |
| Right atrial pressure mmHg | 9 (7–11) |
| Mean PAP mmHg | 51 (46–56) |
| Cardiac index L·m-2 | 2.0 (1.8–2.2) |
| Mixed venous oxygen saturation % | 58 (55–61) |
| Treatment | |
| Oral anticoagulation | 47 (98) |
| Calcium antagonists (sole/combined therapy) | 2 (4)/14 (29) |
| Inhaled iloprost | 32 (67) |
| Bosentan | 6 (13) |
| Continuous intravenous iloprost | 6 (13) |
| Combination of inhaled iloprost and bosentan | 2 (4) |
Data are presented as mean (95% confidence interval) or n (%), unless otherwise stated. MLHF: Minnesota Living with Heart Failure; NYHA/WHO: New York Heart Association/World Health Organization; 6-MWD: 6-min walking distance; PAP: pulmonary arterial pressure. #: n = 44. 1 mmHg = 0.133 kPa.