Table 4—

Summary of studies evaluating effect of fundoplication on respiratory symptoms

First authors [Ref.]Children with medically recalcitrant GOR undergoing fundoplicationPatientsResolution
Jolley 101Mixed group with recurrent aspiration pneumonia, choking and/or chronic cough6192
Mattioli 102Mixed group with recurrent aspiration, lower respiratory tract infections, recurrent pneumonia or chronic cough3080
Kawahara 103Neurologically impaired with recurrent respiratory infections or distress3148#
Esposito 104Repaired oesophageal atresia with recurrent aspiration2186
  • GOR: gastro-oesophageal reflux. #: four subjects required laryngotracheal separation, three required tracheostomy.