Features of Aspergillus-related lung disease in patients with bronchiectasis according to nontuberculous mycobacteria (NTM) lung disease
| NTM lung disease | p-value# | ||
| Yes | No | ||
| Total subjects | 30 | 61 | |
| Eosinophil count/total IgE | |||
| Eosinophilia >0.5 | 2 | 3 | 1.0 |
| IgE >150 | 4 | 14 | 0.27 |
| Size of IgE among positives | 2740±2709 | 835±1520 | 0.08 |
| Positive serology for Aspergillus-related lung disease¶ | |||
| Total patients with positive serology | 10 | 6 | 0.005 |
| Positive A. fumigatus precipitins and RAST | 3 | 1 | 0.10 |
| Positive A. fumigatus precipitins | 10 | 4 | 0.003 |
| 1 line | 2 | 1 | |
| 2 lines | 6 | 3 | |
| 3 lines | 2 | 0 | |
| Positive A. fumigatus RAST | 3 | 2 | 0.32 |
| Radiological features suggestive of Aspergillus-related lung disease | 6 | 0 | 0.003 |
| Invasive aspergillosis/CNPA | 1 | ||
| Probable aspergilloma | 3 | 0 | |
| Definite aspergilloma | 2 | 0 | |
| Clinical and serological features consistent with ABPA | |||
| ABPA | 4 | 3 | 0.2 |
| ABPA, aspergilloma | 1 | 0 | |
Data are presented as n or mean±sd. Ig: immunoglobulin; A. fumigatus: Aspergillus fumigatus; RAST: radioallergosorbent test; CNPA: chronic necrotising pulmonary aspergillosis; ABPA: allergic bronchopulmonary aspergillosis. #: univariate analysis using Chi-squared or Fisher's exact test for contingency tables and unpaired t-test for comparison of means; ¶: see Methods section for details.