Table 2—

Initial antibiotic treatment and mortality rate in chronic obstructive pulmonary disease patients

Antibiotic treatmentSubjectsAnti-pseudomonal activityAPSIATPoor resolutionMortality
β-Lactam plus macrolide93 (52.9)2412.1±9.6111824 (25.8)
β-Lactam alone19 (10.7)17.6±6.5287 (36.8)
β-Lactam plus fluoroquinolone33 (18.8)3312.3±7.50511 (33.3)
Fluoroquinolone alone21 (11.9)2115.7±6.1135 (23.8)
Macrolide alone1 (0.5)019000
Other combinations9 (5.2)120.7±23.3066 (66.6)
Overall176 (100)8012.6±10.1144053
  • Data are presented as n (%), n or mean±sd. APS: acute physiological score of Acute Physiology And Chronic Health Evaluation II score; IAT: inadequate antibiotic treatment.