Relationship between serum high-sensitivity C-reactive protein (hs-CRP) levels and clinical or sputum indices in patients with asthma
| Serum hs-CRP mg·L−1 | ||||
| ICS- | ICS+ | |||
| r | p-value | r | p-value | |
| Subjects n | 22 | 23 | ||
| Age yrs | 0.15 | 0.49 | −0.14 | 0.52 |
| BMI kg·m−2 | 0.36 | 0.10 | 0.27 | 0.20 |
| FEV1 % pred | −0.57 | 0.009 | −0.34 | 0.11 |
| FEV1/FVC % | −0.63 | 0.004 | −0.15 | 0.48 |
| FEF25–75% % pred | −0.51 | 0.020 | −0.13 | 0.55 |
| Disease duration yrs | −0.017 | 0.935 | 0.33 | 0.14 |
| Cell counts in induced sputum# | ||||
| Macrophages cells×105·g−1 | 0.45 | 0.063 | 0.21 | 0.36 |
| Neutrophils cells×105·g−1 | 0.46 | 0.056 | 0.05 | 0.82 |
| Eosinophils cells×105·g−1 | 0.5 | 0.039 | 0.08 | 0.74 |
| Lymphocytes cells×105·g−1 | 0.09 | 0.70 | 0.21 | 0.39 |
ICS: inhaled corticosteroid; BMI: body mass index; FEV1: forced expiratory volume in one second; FVC: forced vital capacity; FEF25–75%: forced mid-expiratory flow; % pred: percentage of the predicted value. #: in 18 ICS- subjects, 22 ICS+ subjects and 14 controls.