Subject characteristics
| Severe COPD | Donors | |
| Males:females n | 11:3 | 4:3 |
| Age yrs | 55±2** | 34±8 |
| FEV1 % pred | 17±2 | |
| FEV1/VC % | 37±4 | |
| Pa,O2mmHg | 78±6# | |
| Pa,CO2mmHg | 49±2# | |
| pH | 7.4±0.1 | |
| DL,CO % pred | 26±6 | |
| KCO % pred | 30±7 | |
| P̄pa mmHg | 26±3 | |
| LVEF % | 66±5 | |
| RVEF % | 50±3 |
Data are presented as mean±sem, unless otherwise stated. COPD: chronic obstructive pulmonary disease; FEV1: forced expiratory volume in one second; % pred: percentage of predicted; VC: vital capacity; Pa,O2: arterial oxygen tension; Pa,CO2: arterial carbon dioxide tension; DL,CO: diffusing capacity of the lung for carbon monoxide; KCO: transfer coefficient of the lung for carbon monoxide; P̄pa: mean pulmonary arterial pressure; LVEF: left ventricular ejection fraction (via right heart catheterisation); RVEF: right ventricular ejection fraction (via ECG). DL,CO, LVEF and RVEF measurements were available in 11 of the 14 patients. #: measured with oxygen supplementation. **: p<0.01 versus donors.