Placebo | Irbesartan | p-value# | |||
Baseline | 4 months | Baseline | 4 months | ||
Haematocrit % | 47.5±2.4 | 48.7±3.0 | 46.4±3.6 | 43.9±4.3** | 0.0001 |
Hb g·dL−1 | 15.7±0.9 | 15.9±1.1 | 15.1±1.3 | 14.2±1.6** | 0.002 |
Sodium mM | 140.1±2.5 | 142.1±3.2* | 140.2±3.0 | 140.2±3.0 | 0.021 |
ALT U·L−1 | 24.2±14.4 | 22.3±13.4 | 18.1±10.2 | 22.0±9.9* | 0.047 |
Data are presented as mean±sd. Hb: haemoglobin; ALT: alanine aminotransferase. For details of correction for multiple comparisons, see Statistical analysis. #: ANOVA for time by treatment interaction. *: p<0.05; **: p<0.001 (ANOVA for time).