Table 1—

Baseline characteristics in patients with obstructive sleep apnoea(OSA) and healthy and obese control subjects

Lean subjectsObese subjectsMild OSAModerate-to-severe OSA
Subjects n12182020
Age yrs47.9±2.248.1±2.450.3±1.549.3±3.5
Blood pressure mmHg
Systolic126.8±3.0130.1±3.3129.4±2.5132.0±3.9
Diastolic73.5±2.172.8±2.675.4±2.076.1±3.0
BMI kg·m-222.9±0.427.7±0.9#27.2±0.728.9±0.6+
Waist cm74.3±3.188.4±1.9#89.5±1.090.5±1.8+
Waist/hip ratio0.78±0.010.89±0.01#0.87±0.010.92±0.02+
Total cholesterol mg·dL-1200.6±7.4201.5±8.8202.0±6.2206.4±8.2
HDL cholesterol mg·dL-145.5±3.346.6±1.741.4±1.4¶,§38.9±1.3+,ƒ
LDL cholesterol mg·dL-1120.0±5.5131.2±3.9135.0±2.5136.1±2.9+
Glucose mg·dL-185.6±7.389.6±8.191.2±6.593.1±8.5
Triglyceride mg·dL-1129.6±10.4170.2±16.4#167.6±13.8178.6±13.8+
FVC L3.51±0.353.45±0.243.42±0.133.43±0.28
FEV1 % pred90.7±2.489.5±2.388.9±2.887.9±3.0
AHI events·h-13.4±0.54.0±0.39.8±2.0¶,§46.5±9.8+,ƒ,##
Sa,O2<90% %TST004.1±3.1¶,§38.9±12.9+,ƒ,##
Lowest Sa,O2 %96.0±2.096.4±1.883.6±6.0¶,§70.9±7.9+,ƒ,##
Arousal index events·h-113.9±7.715.4±9.818.4±4.0¶,§42.3±6.8+,ƒ,##
TST min403.9±90.2411.9±100.1380.0±35.4¶,§328.0±68.1+,ƒ,##
ESS7.3±0.48.2±0.59.8±0.713.1±2.8+,ƒ,##
  • Data are presented as mean±sem, unless otherwise stated. BMI: body mass index; HDL: high-density lipoprotein; LDL: low-density lipoprotein; FVC: forced vital capacity; FEV1: forced expiratory volume in one second; % pred: percentage of predicted; AHI: apnoea–hypopnoea index; Sa,O2: arterial oxygen saturation; TST: total sleep time; ESS: Epworth Sleepiness Scale. #: p<0.01 healthy control versus obese control; : p<0.01 healthy control versus mild OSA; +: p<0.01 healthy control versus moderate-to-severe OSA; §: p<0.01 obese control versus mild OSA; ƒ: p<0.01 obese control versus moderate-to-severe OSA; ##: p<0.01 mild OSA versus moderate-to-severe OSA.