Variables | HR (95% CI) | p-value^{¶} | |

Antibiotics | |||

β-Lactams+macrolides | 1 | ||

β-Lactams | 1.02 (0.58–1.81) | 0.945 | |

Macrolides | 0.62 (0.08–4.66) | 0.638 | 0.268 |

Levofloxacin | 0.26 (0.06–1.12) | 0.069 | |

Other combinations | 1.27 (0.72–2.20) | 0.421 | |

Suspected aspiration | 2.79 (1.55–4.99) | 0.001 | |

Bilateral pneumonia | 1.98 (1.24–3.17) | 0.004 | |

PSI score | |||

I+II+III | 1 | ||

IV | 2.61 (1.25–5.42) | 0.010 | |

V | 3.24 (1.51–6.94) | 0.002 | 0.010 |

Shock | 5.76 (3.41–9.75) | <0.001 | |

HIV infection | 2.06 (1.11–3.83) | 0.022 | |

Renal failure | 1.86 (1.11–3.12) | 0.019 |

HR: hazard ratio; PSI: pneumonia severity index. For the full definition of each variable refer to table 2⇑.

^{#}: n = 638 patients;^{¶}: for those variables with several categories the first column of p-values compares every category of the variable to the reference category. The second column shows the significance of the variable as a whole. HR p-values were calculated using Cox regression models; for further explanations see Methods section.