Group (number) | Subjects n | Age yrs | FEV1 % pred | FVC % pred | W/H % | IgG | Pa IgG AU | i.v. therapy in 2003 days |
Never (1) | 48 | 9.1±0.7 | 101.2±2.2 | 104.6±2.2 | 97.8±2.2 | 906±54 | 2.1±0.7 | 0 (0–0) |
Statistical differences | 4¶ | 3, 4¶ | 3, 4¶ | 4¶ | 4¶ | 3, 4+ | ||
Free of Pa (2) | 16 | 10.0±1.1 | 96.6±4.3 | 103.6±3.1 | 95.8±2.3 | 1121±97 | 3.3±1.2 | 0 (0–26) |
Statistical differences | 4¶ | 1, 4¶ | 1, 4¶ | 4¶ | 4¶ | |||
Intermittent (3) | 24 | 10.4±0.9 | 90.9±3.9 | 95.8±3.4 | 99.6±1.8 | 956±72 | 5.6±1.9 | 8 (0–14.5) |
Statistical differences | 4¶ | 1, 4¶ | 1, 4¶ | 4¶ | 4¶ | 1, 4¶ | 1+ | |
Chronic (4) | 12 | 13.7±1.2 | 73.3±4.7 | 84.6±3.0 | 90.1±3.9 | 1484±137 | 38.5±10.2 | 27 (0–39) |
Statistical differences | 1, 2, 3¶ | 1, 2, 3¶ | 1, 2, 3¶ | 3¶ | 1, 2, 3¶ | 1, 2, 3¶ | 1+ |
Data are presented as mean±sem and median (interquartile range), unless otherwise stated. FEV1: forced expiratory volume in one second; % pred: per cent predicted; FVC: forced vital capacity; W/H: weight for height; Ig: immunoglobulin. #: differences in disease severity markers were more pronounced in the paediatric age group; ¶: using unpaired t-test; +: using Mann–Whitney U-test.