Relationship between baseline variables and change in outcomes
| Δ6MWD % | ΔQuads | ΔSGRQ | |
| Age yrs | −0.1 | −0.0 | 0.2 |
| BMI kg·m−2 | 0.2 | −0.2 | −0.1 |
| Smoking pack-yrs | −0.1 | 0.1 | 0.0 |
| 6MWD % pred | −0.3# | −0.1 | −0.4¶ |
| Quadriceps maximum torque Nms | −0.2 | −0.1 | −0.2 |
| Quadriceps Nms·kg−1×100 | −0.4¶ | −0.1 | −0.1 |
| SGRQ total | 0.2 | −0.1 | −0.0 |
| FEV1 % pred | −0.0 | −0.4¶ | −0.1 |
| FVC % pred | −0.1 | −0.3 | 0.0 |
| MIP % pred | 0.1 | −0.2 | −0.2 |
| MEP % pred | −0.1 | −0.2 | −0.1 |
| V′O2,max kg·L−1·min−1 | −0.1 | 0.0 | −0.2 |
| MVV | −0.0 | −0.3 | −0.2 |
| MVV/V′E | −0.2 | 0.2 | −0.1 |
| Grip % pred | 0.0 | −0.0 | 0.0 |
| Borg score pre-6MWD m | 0.2 | 0.1 | 0.1 |
| Borg score post-6MWD m | −0.2 | 0.1 | 0.2 |
| Sa,O2 pre-6MWD % | −0.4¶ | −0.3 | −0.2 |
| Sa,O2 post-6MWD % | 0.1 | −0.4¶ | −0.2 |
| Heart rate pre-6MWD | −0.4¶ | −0.1 | 0.1 |
| Heart rate post-6MWD | −0.3 | 0.1 | 0.0 |
| COPDSE | −0.3# | 0.1 | −0.0 |
| LCADL | 0.2 | 0.0 | 0.2 |
6MWD: 6-minute walking distance; SGRQ: St George's Respiratory Questionnaire; BMI: body mass index; FEV1: forced expiratory volume in one second; % pred: per cent predicted; FVC: forced vital capacity; MIP: maximal inspiratory pressure; MEP: maximal expiratory pressure; V′O2,max: maximum oxygen consumption; MVV/V′E: maximal voluntary ventilation/ventilation ratio; Sa,O2: arterial oxygen saturation; COPDSE: Chronic Obstructive Pulmonary Disease Self-Efficacy Scale; LCADL: London Chest Activity of Daily Living Scale. Borg pre-6MWD values were log transformed in order to achieve a normal distribution prior to analysis. #: p<0.05; ¶: p≤0.01.