Table 2—

Decrements of forced expiratory volume in one second(FEV1) in male offspring who smoke associated with various definitions of chronic obstructive pulmonary disease (COPD) death in a father compared with such offspring with no parental history of COPD death

Family historyEffect on FEV1 mLp-value
COPD anywhere on the death certificate−235 (−64– −407)0.007
COPD as first cause of death−255 (+36– −546)0.086
COPD anywhere on death certificate and death at <70 yrs−319 (−2– −636)0.049
COPD as first cause of death at <70 yrs−478 (−12– −943)0.044
  • Values given in parentheses are 95% confidence intervals. All values are adjusted for age, height, maternal smoking, pack-yrs of personal smoking, parental social class, parental housing tenure, personal social class and personal housing tenure.