Table 4—

Comparison of dispensed treatments#

GroupOverallp-value
GPGP+SPESPE
Antiasthma-controller therapy
 ICS184 (42.0)311 (49.8)59 (43.1)554 (46.2)0.031
 LABA129 (29.5)221 (35.4)41 (29.9)391 (32.6)0.097
 COMBO LABA-ICS243 (55.5)373 (59.8)97 (70.8)713 (59.5)0.006
 Oral xanthines21 (4.8)51 (8.2)3 (2.2)75 (6.3)0.009
 LTRA90 (20.5)204 (32.7)46 (33.6)340 (28.4)0.000
Controller regimens0.004
 Isolated ICS50 (11.4)48 (7.7)4 (2.9)102 (8.5)
 ICS+LABA (separate medications)60 (13.7)85 (13.6)20 (14.6)165 (13.8)
 COMBO LABA-ICS123 (28.1)142 (22.8)42 (30.7)307 (25.6)
 COMBO ABA-ICS+ICS22 (5.0)33 (5.3)11 (8.0)66 (5.5)
 COMBO LABA-ICS+LTRA43 (9.8)81 (13.0)23 (16.8)147 (12.3)
 Others/none140 (32.0)235 (37.7)37 (27.0)412 (34.4)
Antiasthma reliever medications
 SABA323 (73.7)454 (72.8)79 (57.7)856 (71.4)0.001
 Anticholinergic medication4 (0.9)13 (2.1)0 (0.0)17 (1.4)
 Anticholinergic medication +SABA32 (7.3)61 (9.8)11 (8.0)104 (8.7)0.356
Other medications
 Oral corticosteroids166 (37.9)297 (47.6)52 (38.0)515 (43.0)0.003
 Antitussives131 (29.9)176 (28.2)26 (19.0)333 (27.8)0.042
 Expectorants214 (48.9)357 (57.2)51 (37.2)622 (51.9)0.000
 Antibiotics254 (58.0)397 (63.6)60 (43.8)711 (59.3)0.000
Change of therapy during the past 12 months
 None231 (50.2)239 (36.6)61 (42.7)531 (42.3)0.000
 Addition of medication(s)135 (29.3)251 (38.4)30 (21.0)416 (33.1)0.000
 Suppression of medication(s)56 (12.2)120 (18.4)17 (11.9)193 (15.4)0.009
 Any increase of dosage36 (7.8)95 (14.5)16 (11.2)147 (11.7)0.003
 Any decrease of dosage22 (4.8)51 (7.8)27 (18.9)100 (8.0)0.000
 Total change of therapy34 (7.4)53 (8.1)12 (8.4)99 (7.9)0.881
  • Data are presented as n (%), n = 1,199. #: Presence of medication category in the computerised dispensing record. ICS: inhaled corticosteroids; LABA: long-acting beta agonists; COMBO: combination; LTRA: leucotriene receptor antagonists. SABA: short-acting beta agonists; GP: general practitioner; SPE: specialist.