Table 3—

Effect of Bi-/CPAP therapy on polysomnographic data, lipids and body mass index (BMI) in patients with obstructive sleep apnoea

Untreated OSAAfter 6 months of Bi-/CPAP therapyMean difference (95% CI)p-value
Polysomnography
AHI events·h−132.9±21.52.2±2.3−30.7 (−26.8– −34.6)<0.001
Mean O2 saturation91.4±5.493.9±1.92.8 (3.5–1.5)<0.001
Maximum O2 desaturation79.8±10.688.0±7.18.1 (10.5–5.8)<0.001
Arousal index19.1±8.07.9±6.1−11.2 (−6.1– −16.3)<0.001
Sleep efficiency86.7±11.386.3±13.6−0.4 (2.9– −3.9)0.784
Lipids
Total cholesterol223.5±41.4220.30±39.4−3.4 (3.6– −10.0)0.351
Triglycerides175.1±102.3166.2±87.77−8.6 (6.2– −23.5)0.116
HDL-C46.9±15.849.6±15.252.7 (4.9–0.6)0.013
LDL-C144.5±37.8138.99±37.1−5.5 (2.0– −13.0)0.151
BMI31.6±5.931.4±5.4−0.9 (0.15– −0.6)0.229
  • Data are presented as mean±SD unless otherwise stated. Bi-/CPAP: bilevel or continuous positive airway pressure; CI: confidence interval; AHI: apnoea–hypopnoea index; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol.