Asthma | Post-infectious bronchiolitis obliterans | Control | |
Patients n (M/F) | 30 (17/13) | 28 (16/12) | 25 (12/13) |
Age yrs | 9.5±1.8 | 8.2±1.2 | 9.3±2.9 |
Atopy n (%) | 23 (76.7)¶ | 13 (46.4)+ | 11 (44.0) |
Blood eosinophils µL−1 | 487±332¶ | 248±223+ | 252±132 |
FEV1# methacholine challenge | 91.2±19.9 | 77.6±21.1¶,+ | 95.9±15.2 |
FEV1# AMP challenge | 92.5±16.1 | 78.0±18.9¶,+ | 95.7±14.1 |
Data are presented as mean±sd, unless otherwise stated. M: male; F: female; FEV1: forced expiratory volume in one second; AMP: adenosine 5′-monophosphate. Atopy was defined as the presence of at least one positive reaction (>3 mm weal diameter) to a battery of 12 common airborne allergens. #: pre-test baseline values (% predicted); ¶: p<0.05 versus control group; +: p<0.05 versus asthma group.