Table 3—

Summary of the results of investigations performed

TestSubjects testedAbnormal resultsOther information
IgG, IgA, IgM41/47 (87)5/41 (12)Low IgG, 0.2 g·L−1 below normal (n = 3)
Low IgM, 0.2 g·L−1 below normal (n = 2)
IgG subclasses11/47 (23)3/33 (9)All three abnormal results were normal when repeated
Sweat test30/47 (64)0/30 (0)Equivocal 1/30 (3%)
HRCT scan29/47 (62)15/29 (52)
pH study37/47 (79)25/37 (68)Unsuccessful 2/37 (5)
Cilia34/47 (72)0/34 (0)Nude epithelium 8/34 (24)
FOB#47/47 (100)37/47 (78)
BAL: any result44/47 (94)39/44 (89)
BAL culture+44/47 (94)19/44 (43)
BAL fat-laden macrophages44/47 (93)33/44 (75)Score: mild (n = 23), moderate (n = 8) and severe (n = 2)
BAL inflammation37/47 (79)24/37 (65)Score: eosinophilia (n = 4), neutrophilia (n = 16), combined (n = 4)
EB eosinophilic inflammation36/47 (77)16/36 (44)Score: 0 (n = 20), 1 (n = 6), 2 (n = 6), 3 (n = 3), 5 (n = 1)
EB RBM thickening35/47 (74)10/35 (29)Score: 0 (n = 2), 1 (n = 23), 2 (n = 9), 3 (n = 1)
  • Data are presented as n/n (%). Ig: immunoglobulin; HRCT: high-resolution computed tomography; FOB: fibreoptic bronchoscopy; BAL: bronchoalveolar lavage; EB: endobronchial biopsy; RBM: reticular basement membrane. #: details of abnormalities in the text; : BAL inflammation, fat-laden macrophages or infection; +: BAL with significant bacterial growth.