Table 1—

Investigations performed during an overnight stay in young children with severe recurrent wheeze

Investigation
Day 1Sweat test
 Under oral sedation, if neededHigh-resolution CT chest scan
 Under general anaestheticBlood tests: total IgE, RASTs to food and aeroallergens, IgG, IgA, IgM and IgG subclasses
Nasal ciliary brushings
Fibreoptic bronchoscopy with bronchoalveolar lavage and endobronchial biopsies
Placement of oesophageal pH probe
Day 2Review and discharge
  • CT: computed tomography; Ig: immunoglobulin; RAST: radioallergosorbent test.