Lung function parameters capable of differentiating extrathoracic from intrathoracic obstruction
Extrathoracic obstruction | Intrathoracic obstruction | ||
Fixed | Variable | ||
PEF | Decreased | Normal or decreased | Decreased |
MIF50 | Decreased | Decreased | Normal or decreased |
MIF50/MEF50 | ∼1 | <1 | >1 |
PEF: peak expiratory flow; MIF50: maximum inspiratory flow at 50% of forced vital capacity (FVC); MEF50: maximum expiratory flow at 50% of FVC.