Table. 5—

Multivariate# associations of selected factors with different phenotypes of asthma

Asthma factorWheeze factorShortness of breath factor
ORLower 95% CIUpper 95% CIz-valueORLower 95% CIUpper 95% CIz-valueORLower 95% CIUpper 95% CIz-value
Maternal asthma2.270.952.95 6.191.601.252.05 3.711.521.201.92 3.46
Atopy3.292.783.9113.641.431.221.66 4.611.291.221.49 3.57
BHR7.516.348.9023.272.912.463.4512.442.352.002.7610.45
Current smoking0.870.721.04−1.503.082.603.6513.071.191.121.52 3.44
Ex-smoking0.980.791.22−0.191.241.001.56 1.921.310.991.42 1.86
Age 30–39 yrs0.790.660.95−2.460.840.720.99−2.060.960.821.12−0.54
Age >40 yrs0.850.681.07−1.410.850.691.04−1.581.170.971.40 1.66
Female1.070.911.26 0.771.110.961.28 1.431.381.211.58 4.69
  • OR: odds ratio; CI: confidence interval; BHR: bronchial hyperresponsivness. #: OR calculated using logistic regression, adjusting for centre and all the other variables in the table. : phenotypes based on dichotomised scores from principal component analysis of the 12 questions on asthma symptoms. The first factor corresponds closely to the question on ever asthma, second factor to questions on wheeze, and third factor on questions on chest tightness and shortness of breath.