Table. 1—

Characteristics of several drug susceptibility testing methods

MethodAccuracy %CostSkills/equipmentCoverage
Proportion method>95LowNoAll drugs
BACTEC radiometric>95HighYesMost drugs
Manual MGIT>90MediumNoSeveral drugs
Automated MGIT 960>90HighYesR, H, E, S
E-Test>90MediumNoR, H, E, S
DNA sequencing>90 (for R)HighYesSeveral drugs
Solid-phase hybridization test>95HighYesR
FastPlaque TB>90Low/mediumSome skillR, H
MB/BacT>95HighYesR, H, E, S
ESP System II>93HighYesR, H, E, S
Colorimetric methods>95LowNoMost drugs
Nitrate reduction assay>95LowNoMost drugs
  • MGIT: mycobacteria growth indicator tube; TB: tuberculosis; R: rifampicin; H: isoniazid; E: ethambutol; S: streptomycin.