Hazard ratios for variables in multivariable Cox models excluding and including baseline variables and comorbidities
| Variables | Model A baseline covariables and comorbidities | p-value | Model B baseline covariables and CCI | p-value |
| Age >70 yrs | 1.36 (1.03–1.79) | p = 0.02 | 1.,36 (1.04–1.79) | p = 0.02 |
| T2 | 1.36 (1.05–1.78) | P = 0.01 | 1.33 (1.03–1.72) | p = 0.03 |
| CCI >2 | 1.81 (1.25–2.63) | p = 0.002 | ||
| Cerebrovascular disease | 1.74 (1.009–3.01) | p = 0.04 | ||
| Any prior tumour within 5 yrs of diagnosis | 1.81 (1.25–2.85) | p = 0.008 | ||
| Connective tissue disease | 4.1 (0.97–20.0) | p = 0.055 | ||
| Moderate-to-severe liver disease | 3.3 (1.63–6.8) | p = 0.0009 |
Data are presented as hazard ratio (95% confidence interval). CCI: Charlson comorbidity index.